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Veterans and Agent Orange: Update 2002

Released:
January 16, 2003
Type:
Consensus Report
Topic(s):
Environmental Health, Veterans Health
Activity:
Health Effects in Vietnam Veterans of Exposure to Herbicides (Agent Orange)
Board(s):
Board on Population Health and Public Health Practice

This report, Veterans and Agent Orange: Update 2002, is the fourth in a series examining the impact of chemical defoliants, including Agent Orange, and their contaminants on human health. In previous updates on the health risk to veterans posed by exposure to Agent Orange and other chemicals used in Vietnam, all forms of leukemia were considered collectively when examining research on links between exposure to herbicides and the risk for cancer. The combined evidence was found to be inadequate or insufficient to determine whether any association exists between leukemia and exposure to the herbicides or contaminants in them. However, a recent re-examination of the evidence revealed sufficient evidence of an association between exposure to herbicides sprayed during the Vietnam War and the risk for development of a specific form of leukemia - chronic lymphocytic leukemia (CLL) - in veterans.

Although classified as a form of leukemia, CLL shares many traits with Hodgkin's disease and non-Hodgkin's lymphoma, both of which previously have found to be positively associated with herbicide exposure. Both CLL and lymphomas originate from malignant B-cells, and CLL can transform into an aggressive non-Hodgkin's lymphoma known as Richter's Syndrome.

The report made recommendations for future scientific studies on the health effects of herbicides and contaminants used in Vietnam, including further investigation of glioblastomas and astrocytomas.


Other Reports by this Activity

  • Veterans and Agent Orange: Update 2008 From 1962 to 1971, US military sprayed herbicides over Vietnam. Because of continuing uncertainty about the long-term health effects of the sprayed herbicides on Vietnam veterans, Congress passed the Agent Orange Act of 1991. The legislation directed the Secretary of Veterans Affairs to request the Institute of Medicine to perform a comprehensive evaluation of scientific and medical information regarding the health effects of exposure to Agent Orange and other herbicides used in Vietnam. Veterans and Agent Orange: Update 2008 is the eighth report in this series.
    Released: July 24, 2009
  • Veterans and Agent Orange: Update 2006 Because of continuing uncertainty about the long-term health effects of the sprayed herbicides on Vietnam veterans, Congress passed the Agent Orange Act of 1991. The legislation directed the Secretary of Veterans Affairs to request the Institute of Medicine of the National Academy of Sciences (NAS) to perform a comprehensive evaluation of scientific and medical information regarding the health effects of exposure to Agent Orange and other herbicides used in Vietnam. Mandated updates to the original study were to be conducted every 2 years for 10 years. Veterans and Agent Orange, Update 2006 is the seventh report in this series.
    Released: July 27, 2007
  • Veterans and Agent Orange: Update 2004 Agent Orange and other herbicides were used as defoliants in the Vietnam War. Under a Congressional mandate, the Institute of Medicine (IOM) of the National Academies conducted a comprehensive review of the scientific literature to determine whether Vietnam veterans may be experiencing health effects associated with exposure to those herbicides or chemicals contaminating them. IOM's study has been updated every two years, and Veterans and Agent Orange: Update 2004 is the latest report in that series.
    Released: March 3, 2005

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