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From Molecules to Minds: Challenges for the 21st Century. Workshop Summary

Released:
September 29, 2008
Type:
Workshop Summary
Topics:
Biomedical and Health Research, Substance Abuse and Mental Health, Diseases, Aging, Public Health, Quality and Patient Safety
Activity:
Forum on Neuroscience and Nervous System Disorders
Board:
Board on Health Sciences Policy

Note: Workshop Summaries contain the opinion of the presenters, but do NOT reflect the conclusions of the IOM. Learn more about the differences between Workshop Summaries and Consensus Reports.

Neuroscience has made phenomenal advances over the past 50 years and the pace of discovery continues to accelerate. On June 25, 2008, the IOM Forum on Neuroscience and Nervous System Disorders hosted more than 70 of the leading neuroscientists in the world, for a workshop titled From Molecules to Minds: Challenges for the 21st Century. The objective of the workshop was to explore a set of common goals or “Grand Challenges” posed by participants that could inspire and rally both the scientific community and the public to consider the possibilities for neuroscience in the 21st century. The progress of the past in combination with new tools and techniques, such as neuroimaging and molecular biology, has positioned neuroscience on the cusp of even greater transformational progress in our understanding of the brain and how its inner workings result in mental activity. This workshop summary highlights the important issues and challenges facing the field of neuroscience as presented to those in attendance at the workshop, as well as the subsequent discussion that resulted. As a result, three overarching Grand Challenges emerged:

  • How does the brain work and produce mental activity? How does physical activity in the brain give rise to thought, emotion, and behavior?
  • How does the interplay of biology and experience shape our brains and make us who we are today?
  • How do we keep our brains healthy? How do we protect, restore, or enhance the functioning of our brains as we age?

Other Reports by this Activity

  • Glutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System – A Workshop Problems with how the neurotransmitter glutamate functions in the brain have been linked to a wide variety of disorders, including schizophrenia, Alzheimer’s, substance abuse, and traumatic brain injury. Efforts to understand, treat, and prevent glutamate-related disorders can be aided by the identification of valid biomarkers. The IOM’s Forum on Neuroscience and Nervous System Disorders held a workshop June 21-22, 2010, to explore ways to accelerate the development, validation, and implementation of such biomarkers.
    Released: June 8, 2011
  • Future Opportunities to Leverage the Alzheimer's Disease Neuroimaging Initiative - Workshop Summary Nearly 5.3 million Americans are living with Alzheimer’s disease, and 26.6 million people are affected worldwide. The Alzheimer’s Disease Neuroimaging Initiative (ADNI), a public-private partnership, provides a publicly available, international database of clinical and imaging data to foster research and collaboration on Alzheimer’s research worldwide. The IOM held a workshop on July 12, 2010, to explore opportunities to use information from and partnerships formed because of ADNI to continue to improve the understanding and treatment of Alzheimer’s disease.
    Released: December 10, 2010
  • Sex Differences and Implications for Translational Neuroscience Research - Workshop Summary Biological differences between the sexes influence not only individual health but also public health, biomedical research, and health care. The IOM held a workshop March 8-9, 2010, to discuss sex differences and their implications for translational neuroscience research, which bridges the gap between scientific discovery and application.
    Released: December 10, 2010

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Supplemental Materials

  • Workshop Highlights

    From Molecules to Minds: Challenges for the 21st Century. Summary of a Workshop. Published: 2008