8:55 a.m.  Charge to Participants and Workshop Scope
Donald Mattison, M.D., Member, Roundtable on Environmental Health Sciences, Research, and Medicine, Medical Director, March of Dimes

Session I:  Clinical and Public Health Aspects of Prematurity: Causes, Interventions, and Consequences

Moderator:  Jeannette Rogowski, Ph.D., Senior Economist, RAND Graduate School
 

9:30 a.m.  Causes and Mechanisms of Premature Labor
James M. Roberts, M.D., Senior Scientist and Director, Magee-Women's Research Institute 
 

10:00 a.m.  Clinical and Public Health Interventions: Why Nothing Has Worked
Robert L. Goldenberg, M.D., Charles E. Flowers Professor, Department of Obstetrics and Gynecology, University of Alabama at Birmingham

Questions and Answers 

10:30 a.m.  Long-Term Outcomes of Preterm Infants 
Maureen Hack, M.D., Professor of Pediatrics, Rainbow Babies and Children's Hospital, University Hospitals of Cleveland
 

11:00 p.m.  Break

Session II:  Environmental Causes of Prematurity

Moderator:  E. Albert Reece, M.D. , Abraham Roth Professor and Chairman, Department of Obstetrics and Gynecology and Reproductive Sciences, Temple University School of Medicine

11:30 a.m.  A Framework for Social and Cultural Determinants of Prematurity
Carol Hogue, Ph.D., M.P.H., Terry Professor of Maternal and Child Health, Rollins School of Public Health, Emory University

Questions and Answers

12:00 p.m.  Toxic Social Environment: a Factor in Preterm Birth?
Janet W. Rich-Edwards, Sc.D., Assistant Professor, Department of Ambulatory Care and Prevention, Harvard Medical School

12:30 p.m.  Lunch

Session III:  Environmental Causes of Prematurity: the Role of Environmental Toxicants

Moderator:  Donna S. Dizon-Townson, M.D., Co-Director, Perinatal Center, Utah Valley Regional Medical Center\

1:30 p.m.  Epidemiologic Clues to the Study of the Environment and Preterm Birth
David Savitz, Ph.D., Professor and Chair in Epidemiology, School of Public Health, University of North Carolina at Chapel Hill

2:00 p.m.  Exposures to Environmental Agents and Preterm Delivery
Matthew Longnecker, M.D., Intramural Scientist, National Institute of Environmental Health Sciences

2:30 p.m.  Gene-Environment Interactions and Preterm Delivery
Xiaobin Wang, M.D., M.P.H., Sc.D., Associate Professor, Boston University School of Medicine

3:00 p.m.  Break

Session IV: Experimental and Laboratory Approaches to Analyzing Prematurity

Moderator:  John R. G. Challis, Ph.D. D.Sc, FIBiol FRCOG FRSC, Scientific Director, CIHR, Institute of Human Development, Child and Youth Health

3:30 p.m.  Current Approaches to Reproductive and Developmental Toxicity Testing and Risk Assessment
Carole Kimmel, Ph.D., Senior Scientist, Environmental Protection Agency

4:00 p.m.  Evaluating Chemical Agents for Potential Hazards in Reproduction
Jack B. Bishop, Ph.D., Research Scientist, NIEHS

4:30 p.m.  Assessment and Relevance of Environmental Chemical Effects on Uterine Muscle
Rita Loch-Caruso, Ph.D., Professor and Director of Toxicology, University of Michigan

Wednesday,  October 3, 2001

8:30 a.m.  Welcome Back
Lynn Goldman, M.D., Vice-Chair, Roundtable on Environmental Health Sciences, Research, and Medicine Professor, Johns Hopkins University, School of Public Health

Session V:  Biological Processes that Influence Prematurity

Moderator:  Lynne Wilcox, M.D., Director, Division of Reproductive Health, CDC

8:45 a.m.  Species Differentiation and Animal Models of Parturition 
Peter W. Nathanielsz, Ph.D., James Law Professor of Reproductive Physiology, Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University

9:15 a.m.  Function of Steroids in Parturition and Preterm Labor
William Gibb, Ph.D., Professor, University of Ottawa, Canada

9:45 a.m.  Regulation and Assessment of Uterine Contractility and Cervical Ripening During Pregnancy
Robert E. Garfield, Ph.D., Professor and Director, Division of Reproductive Sciences, Department of Obstetrics and Gynecology, University of Texas Medical Branch

10:15 a.m.  Molecular Mechanisms and Cellular Signaling Pathways Associated with Parturition
Barbara Sanborn, Ph.D., Professor, Department of Biochemistry and Molecular Biology, University of Texas Houston Medical School

10:45 a.m.  Break

11:00 a.m.  Models to Study the Actions of Uterine Lymphocytes during Pregnancy
B. Anne Croy, Ph.D., Professor, Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada

11:30 a.m.  Role of Nitric Oxide in Uterine Activity and Premature Parturition
Chandrasekhar Yallampalli, D.V.M., Ph.D., Professor, Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Texas

12:00 p.m.  Fetal Size and Preterm Birth
Stephen J. Lye, Ph.D., Professor and Joint Head, Program in Development and Fetal Health, Samuel Lunenfeld Research Institute, Mount Sinai Hospital and the Departments of Obstetrics and Gynecology and Physiology, University of Toronto

12:30 p.m.  Lunch

Session VIII:   Discussion 

1:30 p.m.  Summation of the workshop
Donald Mattison, M.D., Member, Roundtable on Environmental Health Sciences, Research, and Medicine, Medical Director, March of Dimes

2:00 p.m.  Panel Discussion

Woodie Kessel, M.D., M.P.H., Assistant Surgeon General, U.S. Department of Health and Human Services

Mark Klebanoff, M.D., Director, Division of Epidemiology, Statistics and Prevention Research, NICHD

Allen J. Wilcox, M.D., Ph.D., Chief of Epidemiology Branch, Environmental Diseases & Medicine Program, Division of Intramural Research, National Institute of Environmental Health Sciences

Daniel Krewski, Ph.D., Professor and Director, R. Samuel McLaughlin Center for Population Health Risk Assessment, University of Ottawa, Canada

Carole Kimmel, Ph.D., Senior Scientist, National Center for Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency (EPA)

Charles J. Lockwood, M.D., Professor and Chairman, Department of Obstetrics and Gynecology, New York University School of Medicine

Karla H. Damus, Ph.D, R.N., Director, Community Programs, Department of Obstetrics and Gynecology and Women’s Health, Albert Einstein School of Medicine

Fernando Guerra, M.D., Director of Health, San Antonio Metropolitan Health District, San Antonio, Texas

Catherine Spong, M.D., Chief, Pregnancy and Perinatology Branch, NICHD, NIH