In this final report, the committee concludes, on the basis of its review of the contractor’s final report and all previous work, that the Columbia University researchers have satisfactorily completed the research project as defined in their proposal and modified in consultation with the committee. It also affirms all the findings and conclusions reached in its own Interim Report (IOM, 2003). The Interim report concluded that a valid exposure reconstruction model for wartime herbicide exposures of US veterans of Vietnam is feasible and therefore recommended that the Department of Veterans Affairs and other government agencies facilitate additional epidemiologic studies of veterans by non-governmental organizations and independent researchers.