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The Committee on Assessing Interactions Among Social, Behavioral, and Genetic Factors in Health held a workshop in the Congressional Room at the Washington Terrace Hotel on June 16, 2005. Below is the agenda that was used for the workshop.
The Washington Terrace Hotel is located at 1515 Rhode Island Ave., NW, Washington, DC, 20005.
Workshop Agenda
June 16, 2005
9:30-9:45 Welcome and Introductions
Dan Blazer, Chair
9:45-10:05 Overview of social variables and their measurement
Ana Diez-Roux, M.D., Ph.D., University of Michigan
- How do social science researchers define "social environment"?
- What are the social variables researchers use to measure the social environment?
- How are these social variables measured? What surveys and methodologies are being used?
10:05-10:25 Conceptualizing social variables to facilitate and promote gene/environment research.
Eileen Crimmins, Ph.D., USC
Slides
- What are the potential pathways through which the social environment and genes interact?
- What are some ways researchers might measure the social environment's impact on genes, and vice versa?
- What methods are currently being used to study the social environment that could provide models for genetic research?
- What do we know about the connection between social environment and psychosocial variables?
- What are the models currently being used to measure the interaction between social environment and behavior?
- What are the models currently being used to measure the interaction between social environment and health outcomes?
10:25-11:00 Discussion
11:00-11:20 Overview of genetic variables and their measurement
Sharon Kardia, Ph.D., University of Michigan, Panel Member
Slides
11:20-11:45 Discussion
11:45-1:00 LUNCH
1:00-3:15 Panel on Epigenetics
1:00-1:20 Gene expression over time
Ming D. Li, Ph.D., University of Texas Health Science Center
Slides
- How is gene expression monitored over time?
- What is the impact on key tissues (e.g., brain tissue relevant to neurobehavioral traits, tumor tissue relevant to cancer, etc)?
- What social variables may result in modification of gene expression over time?
- What are the main analysis methods for investigating gene expression over time in order to understand social environment-by-gene interactions?
- What are the social implications of variable gene expression over time?
1:20-1:40 Epigenetic phenomenon: How to approach mechanisms by which social
variables influence gene expression
Art Beaudet, M.D., Baylor College of Medicine
Slides
- What is epigentic phenomenon?
- What are the implications for imprinting?
- How do epigenetics work through parental influence to execute the human genome?
- Monozygotic twin variation, etc.
- How do environmental change and social variables influence variable expression?
1:40-2:00 Genetics of Ethnic Populations
Sharon Kardia, Ph.D., Panel member
Slides
- What do we know about the genetics of race?
- Where does it get confounced when we want to study the interactions among social, behavioral, and genetic factors?
2:00-2:20 Implications of Genetics of Ethnic Populations for Common Disease
Keith Whitfield, PhD., Panel member
Slides
- What are the implications of these difficulties as they relate to social, behavioral, and genetic interactions for common diseases?
2:20-2:45 Animal models: How do social systems regulate physiological systems and gene functions?
John Sheridan, Ph.D., Ohio State University
Slides
- How do social systems regulate pyisiological systems and gene functions?
2:45-3:30 Discussion
3:30 Workshop Adjourns.
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