Agenda: International Symposium
TUESDAY, JULY 15, 2003
8:00 AM
WELCOME REMARKS
Jerome Strauss, M.D., Ph.D., University of Pennsylvania
INTRODUCTION TO SYMPOSIUM
Allan Rosenfield, M.D., Columbia University
8:30 AM
DISCOVERY APPROACH TO TARGET SELECTION AND VALIDATION
Moderator: Robert Braun, Ph.D., University of Washington
Moderator: Martin Matzuk, M.D., Ph.D., Baylor College of Medicine
Insights from the testicular transcriptome: Michael Griswold, Ph.D., Washington State University
Proteomics and the discovery of contraceptive drug and vaccine targets: John C. Herr, Ph.D., University of Virginia
Toward a comprehensive analysis of the genetic control of male fertility: Barbara Wakimoto, Ph.D., University of Washington
10:00 AM
BREAK
10:15 AM
Towards the genetics of mammalian reproduction: Induction and mapping of gametogenesis mutants in mice: John Schimenti, Ph.D., The Jackson Laboratory
Model organisms: The use of xenopus laevis as a potential model for contraceptive research: Laurence D. Etkin, Ph.D., MD Anderson Cancer Center
Trapping participants of the oocyte-granulosa cell regulatory loop as potential contraceptive targets: John Eppig, Ph.D., The Jackson Laboratory
11:15 AM
FROM TARGET SELECTION TO PRODUCT DEVELOPMENT
Moderator: Gregory S. Kopf, Ph.D., Wyeth Research
Charles Grudzinskas, Ph.D., Drug Development Consultant
12:15 PM
LUNCH
1:15 PM
FUNCTIONAL TARGETS FOR CONTRACEPTION
Moderator: Linda Giudice, Ph.D., Stanford University
Moderator: Gregory S. Kopf, Ph.D., Wyeth Research
Leptin peptide antagonists: Down-regulation of leptin actions in embryo implantation: Ruben Gonzalez, Ph.D., Boston Biomedical Research Institute
Gamete membran fusion: A genetic approach: Diana Myles, Ph.D., University of California, Davis
Using chemical genetics to study regulators of fertility: Caroline Shamu, Ph.D., Harvard Medical School
2:45 PM
BREAK
3:00 PM
SMALL GROUP DISCUSSIONS
STD Prevention and Contraception: Should research be pursued jointly or separately?
Moderator: Nancy Padian, Ph.D., University of California, San Francisco
Target Selection: What criteria should be used to select promising targets?
Moderator: Jerome Strauss, M.D., Ph.D., University of Pennsylvania
Adoption of Contraceptives: What are the challenges associated with adopting contraceptives and how can they be overcome?
Moderator: Jacqueline Darroch, Ph.D., Alan Guttmacher Institute
Immunological Approaches and Contraceptive Research: What is the future outlook?
Moderator: Michael Harper, Ph.D., Sc.D., CONRAD
Evaluation of Contraceptives: What are the obstacles to preclinical evaluation and proof of concept in contraceptive development and how can they be overcome?
Moderators: Marlene Cohen, Ph.D., Independent Consultant; Ruth Merkatz, Ph.D., R.N., Pfizer
5:00 PM
ADJOURN
WEDNESDAY, JULY 16
8:00 AM
ADVANCES IN MATERIALS SCIENCE
Moderator: Lisa Brannon-Peppas, Ph.D., University of Texas, Austin
Overview of controlled release: Thomas Tice, Ph.D., Southern Research Institute
An overview of controlled release technology in contraceptive devices: Camilla Santos, Ph.D., Spherics, Inc
Development of injectible, biodegradable microsphere products for sustained drug delivery: Mark Tracy, Ph.D., Alkermes, Inc.
9:30 AM
BREAK
9:45 AM
CASE STUDIES IN CONTRACEPTIVE DEVELOPMENT
Moderator: Anna Glasier, M.D., University of Edinburgh
Contraceptive microbicide development: Lessons from mucosal ecology: Kevin Whaley, Ph.D., Epicyte Pharmaceutical, Inc.; Johns Hopkins University; ReProtect, Inc.; Mapp Pharmaceutical, Inc.
Male hormonal contraception: William Bremner, M.D., Ph.D., University of Washington
Biosyn/C31G: Anne Marie Corner, M.B.A., Biosyn; Daniel Malamud, Ph.D., University of Pennsylvania; Kurt Barnhart, M.D., University of Pennsylvania
11:45 AM
LUNCH
12:45 PM
CHALLENGES AND SOLUTIONS IN CONTRACEPTIVE PRODUCT DEVELOPMENT AND EVALUATION
Moderator: Regine Sitruk-Ware, M.D., Population Council
Challenges and solutions in contraceptive product development and evaluation: A U.S. regulatory perspective: Lisa Rarick, M.D.
Giving choices in family planning: Paul F.A. Van Look, M.D., Ph.D., World Health Organization
Applicability of contraceptive research to the needs of women in developing countries: Ellen Elizabeth Hardy, Ph.D., Universidade Estadul de Campinas, Brazil
Exploring user issues that affect contraceptive development and introduction: Kim Dickson-Tetteh, M.D., Reproductive Health Research Unit, South Africa
2:45 PM
BREAK
3:00 PM
PANEL DISCUSSION
Moderator: Nancy Padian, Ph.D., University of California, San Francisco
Diana Blithe, Ph.D., National Institute of Child Health and Human Development, National Institutes of Health
Laneta Dorflinger, Ph.D., Family Health International
Henry Gabelnick, Ph.D., CONRAD
Maurizio Macaluso, M.D., Dr.P.H., Centers for Disease Control and Prevention
Jeffrey Spieler, U.S. Agency for International Development
4:30 PM
SUMMARY
Jerome Strauss, M.D., Ph.D., University of Pennsylvania
5:00 PM
ADJOURN
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